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Berberine
Berberine
Berberine
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Berberine
Berberine
Berberine

4 Leaf Nutrition

Berberine

Formulated with 1200 mg of pure Berberine per serving to support healthy glucose levels*

$39.99
Supplement Facts

3rd Party 
Tested

Vegan /
Vegetarian

Made in the
USA

NonGMO

Discover the Benefits

  • Berberine works by activating AMP-activated protein kinase (AMPK), supporting glucose metabolism, insulin sensitivity, and lipid metabolism*
  • Promotes heart health and improves cholesterol levels*
  • Supports gut health by positively influencing gut microbiota and strengthening the gut barrier*
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Enhances insulin sensitivty*

Pro-inflammatory and gut health* 

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Reduces LDL Cholesterol*

Regulates insulin and leptin*

Support you can feel

Blood Sugar Support*

By activating AMP-activated protein kinase (AMPK), Berberine helps cells absorb glucose and reduces glucose production in the liver. Research indicates that Berberine's blood sugar-lowering effects are comparable to Metformin.

Yin, J., Xing, H., & Ye, J. (2008). Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism: clinical and experimental, 57(5), 712–717

https://doi.org/10.1016/j.metabol.2008.01.013
Heart Health Support*

Recent research suggests Berberine is effective in promoting heart health by lowering bad cholesterol, increasing good cholesterol, reducing triglycerides, and improving heart function. These benefits help manage lipids and inflammation, reducing the risk of heart disease.


Xia, L. M., & Luo, M. H. (2016). Study progress of berberine for treating cardiovascular disease. Chronic diseases and translational medicine, 1(4), 231–235.

https://doi.org/10.1016/j.cdtm.2015.11.006
Gut Health Support*

Berberine helps balance your gut by eliminating harmful bacteria and promoting beneficial ones. It's a natural remedy for digestive issues like diarrhea and inflammatory bowel disease (IBD). By maintaining a healthy gut, berberine aids digestion and nutrient absorption. Studies have shown how different doses of berberine affect gut microbiota and its potential clinical benefits, providing a basis for its future use in clinical treatments.


Yang, F., Gao, R., Luo, X., Liu, R., & Xiong, D. (2023). Berberine influences multiple diseases by modifying gut microbiota. Frontiers in nutrition, 10, 1187718. 

https://doi.org/10.3389/fnut.2023.1187718

Berberis Aristata (plant)

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Inside Berberine HCl

  • Our Berberine supplement features Berberine HCl, extracted from the bark of Berberis Aristata.
  • Traditionally used in Ayurvedic and Chinese medicine, Berberine has been recognized for centuries for its therapeutic properties, including support for glucose metabolism and heart health.
  • The Hydrochloride (HCl) form enhances absorption and stability, ensuring you receive the maximum effectiveness with each dose.

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References

1. Yin, J., Xing, H., & Ye, J. (2008). Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism: clinical and experimental, 57(5), 712–717

https://doi.org/10.1016/j.metabol.2008.01.013

2.
Xia, L. M., & Luo, M. H. (2016). Study progress of berberine for treating cardiovascular disease. Chronic diseases and translational medicine, 1(4), 231–235.

https://doi.org/10.1016/j.cdtm.2015.11.006

3. 
Yang, F., Gao, R., Luo, X., Liu, R., & Xiong, D. (2023). Berberine influences multiple diseases by modifying gut microbiota. Frontiers in nutrition, 10, 1187718.

https://doi.org/10.3389/fnut.2023.1187718

Why Choose Us

At 4 Leaf Nutrition, we are dedicated to providing natural, clean supplements designed to simplify your life. We care deeply about health and well-being, offering support through our dietary supplements. Our commitment to our customers is reflected in our Vegan/Vegetarian, non-GMO products, manufactured in GMP-certified facilities in the USA and adhering to strict Good Manufacturing Practices. Additionally, each supplement undergoes Third-Party Testing to ensure purity, potency, and safety, giving you peace of mind while maximizing the benefits of each supplement.